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When the inhibitor tells more than the substrate: the cyanide-bound state of a carbon monoxide dehydrogenase
Carbon monoxide dehydrogenase (CODH) is a key enzyme for reversible CO interconversion. To elucidate structural and mechanistic details of CO binding at the CODH active site (C-cluster), cyanide is frequently used as an iso-electronic substitute and inhibitor. However, previous studies revealed conf...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005268/ https://www.ncbi.nlm.nih.gov/pubmed/29997808 http://dx.doi.org/10.1039/c5sc04554a |