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Autoinflammatory Reaction in Dogs Treated for Cancer via G6PD Inhibition
Glucose-6-phosphate dehydrogenase (G6PD) is an oncoprotein that is overexpressed in cancer cells to provide the NADPH required for their increased anabolism. NADPH, sourced from G6PD fuels nucleotide biosynthesis, maintains redox potential of thioredoxin and glutathione and drives the mevalonate pat...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005277/ https://www.ncbi.nlm.nih.gov/pubmed/29955429 http://dx.doi.org/10.1155/2017/4275305 |