Current understanding of reovirus oncolysis mechanisms

Mammalian orthoreovirus (reovirus) is under development as a cancer virotherapy. Clinical trials demonstrate that reovirus-based therapies are safe and tolerated in patients with a wide variety of cancers. Although reovirus monotherapy has proven largely ineffective, reovirus sensitizes cancer cells...

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Detalles Bibliográficos
Autores principales: Phillips, Matthew B, Stuart, Johnasha D, Rodríguez Stewart, Roxana M, Berry, Jameson TL, Mainou, Bernardo A, Boehme, Karl W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005300/
https://www.ncbi.nlm.nih.gov/pubmed/29942799
http://dx.doi.org/10.2147/OV.S143808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005300/
https://www.ncbi.nlm.nih.gov/pubmed/29942799
http://dx.doi.org/10.2147/OV.S143808

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