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Current understanding of reovirus oncolysis mechanisms

Mammalian orthoreovirus (reovirus) is under development as a cancer virotherapy. Clinical trials demonstrate that reovirus-based therapies are safe and tolerated in patients with a wide variety of cancers. Although reovirus monotherapy has proven largely ineffective, reovirus sensitizes cancer cells...

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Detalles Bibliográficos
Autores principales:	Phillips, Matthew B, Stuart, Johnasha D, Rodríguez Stewart, Roxana M, Berry, Jameson TL, Mainou, Bernardo A, Boehme, Karl W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005300/ https://www.ncbi.nlm.nih.gov/pubmed/29942799 http://dx.doi.org/10.2147/OV.S143808

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