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Mutation EthA(W21R) confers co-resistance to prothionamide and ethionamide in both Mycobacterium bovis BCG and Mycobacterium tuberculosis H37Rv

Ethionamide (ETA) and prothionamide (PRO) are interchangeably used in tuberculosis (TB) chemotherapy regimens. Subtle discrepancies between biochemical and genetic information on the modes of sensitivity and resistance of isoniazid (INH) and ETA warrants further studies. We report a new mutation – E...

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Detalles Bibliográficos
Autores principales: Mugweru, Julius, Liu, Jianxiong, Makafe, Gaelle, Chiwala, Gift, Wang, Bangxing, Wang, Changwei, Li, Xinjie, Tan, Yaoju, Yew, Wing Wai, Tan, Shouyong, Zhang, Tianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005328/
https://www.ncbi.nlm.nih.gov/pubmed/29942141
http://dx.doi.org/10.2147/IDR.S163965