Germline mutations and somatic inactivation of TRIM28 in Wilms tumour

Wilms tumour is a childhood tumour that arises as a consequence of somatic and rare germline mutations, the characterisation of which has refined our understanding of nephrogenesis and carcinogenesis. Here we report that germline loss of function mutations in TRIM28 predispose children to Wilms tumo...

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Detalles Bibliográficos
Autores principales: Halliday, Benjamin J., Fukuzawa, Ryuji, Markie, David M., Grundy, Richard G., Ludgate, Jackie L., Black, Michael A., Skeen, Jane E., Weeks, Robert J., Catchpoole, Daniel R., Roberts, Aedan G. K., Reeve, Anthony E., Morison, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005459/
https://www.ncbi.nlm.nih.gov/pubmed/29912901
http://dx.doi.org/10.1371/journal.pgen.1007399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005459/
https://www.ncbi.nlm.nih.gov/pubmed/29912901
http://dx.doi.org/10.1371/journal.pgen.1007399

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