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Parameter sensitivity analysis for a stochastic model of mitochondrial apoptosis pathway
Understanding how gene alterations induce oncogenesis plays an important role in cancer research and may be instructive for cancer prevention and treatment. We conducted a parameter sensitivity analysis to the mitochondrial apoptosis model. Both a nonlinear bifurcation analysis of the deterministic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005494/ https://www.ncbi.nlm.nih.gov/pubmed/29912904 http://dx.doi.org/10.1371/journal.pone.0198579 |