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Parameter sensitivity analysis for a stochastic model of mitochondrial apoptosis pathway

Understanding how gene alterations induce oncogenesis plays an important role in cancer research and may be instructive for cancer prevention and treatment. We conducted a parameter sensitivity analysis to the mitochondrial apoptosis model. Both a nonlinear bifurcation analysis of the deterministic...

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Detalles Bibliográficos
Autores principales:	Chen, Xianli, Li, Xiaoguang, Zhao, Wei, Li, Tiejun, Ouyang, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005494/ https://www.ncbi.nlm.nih.gov/pubmed/29912904 http://dx.doi.org/10.1371/journal.pone.0198579

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