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Characterisation of the hepatitis B virus cross-species transmission pattern via Na(+)/taurocholate co-transporting polypeptides from 11 New World and Old World primate species

The hepatic Na(+)/taurocholate co-transporting polypeptide (NTCP in man, Ntcp in animals) is the high-affinity receptor for the hepatitis B (HBV) and hepatitis D (HDV) viruses. Species barriers for human HBV/HDV within the order Primates were previously attributed to Ntcp sequence variations that di...

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Detalles Bibliográficos
Autores principales: Müller, Simon F., König, Alexander, Döring, Barbara, Glebe, Dieter, Geyer, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005513/
https://www.ncbi.nlm.nih.gov/pubmed/29912972
http://dx.doi.org/10.1371/journal.pone.0199200