Cargando…
Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domain
The human dopamine transporter (hDAT) is located on presynaptic neurons, where it plays an essential role in limiting dopaminergic signaling by temporarily curtailing high neurotransmitter concentration through rapid re-uptake. Transport by hDAT is energized by transmembrane ionic gradients. Dysfunc...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005636/ https://www.ncbi.nlm.nih.gov/pubmed/29874235 http://dx.doi.org/10.1371/journal.pcbi.1006229 |