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Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domain

The human dopamine transporter (hDAT) is located on presynaptic neurons, where it plays an essential role in limiting dopaminergic signaling by temporarily curtailing high neurotransmitter concentration through rapid re-uptake. Transport by hDAT is energized by transmembrane ionic gradients. Dysfunc...

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Detalles Bibliográficos
Autores principales: Jayaraman, Kumaresan, Morley, Alex N., Szöllősi, Daniel, Wassenaar, Tsjerk A., Sitte, Harald H., Stockner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005636/
https://www.ncbi.nlm.nih.gov/pubmed/29874235
http://dx.doi.org/10.1371/journal.pcbi.1006229