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Direct Structural Annotation of Membrane Protein Aggregation Loci using Peptide-Based Reverse Mapping

[Image: see text] Membrane protein aggregation is associated with neurodegenerative diseases. Despite remarkable advances to map protein aggregation, molecular elements that drive the structural transition from functional to amyloidogenic β-sheet polymers remain elusive. Here, we report a simple and...

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Detalles Bibliográficos
Autores principales: Lella, Muralikrishna, Mahalakshmi, Radhakrishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005643/
https://www.ncbi.nlm.nih.gov/pubmed/29763546
http://dx.doi.org/10.1021/acs.jpclett.8b00953