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Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION
Macromolecular complexes that exhibit continuous forms of structural flexibility pose a challenge for many existing tools in cryo-EM single-particle analysis. We describe a new tool, called multi-body refinement, which models flexible complexes as a user-defined number of rigid bodies that move inde...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005684/ https://www.ncbi.nlm.nih.gov/pubmed/29856314 http://dx.doi.org/10.7554/eLife.36861 |