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Autosomal dominant cerebellar ataxias: Imaging biomarkers with high effect sizes
OBJECTIVE: As gene-based therapies may soon arise for patients with spinocerebellar ataxia (SCA), there is a critical need to identify biomarkers of disease progression with effect sizes greater than clinical scores, enabling trials with smaller sample sizes. METHODS: We enrolled a unique cohort of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005808/ https://www.ncbi.nlm.nih.gov/pubmed/29922574 http://dx.doi.org/10.1016/j.nicl.2018.06.011 |