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SIRT2 Promotes the Migration and Invasion of Gastric Cancer through RAS/ERK/JNK/MMP-9 Pathway by Increasing PEPCK1-Related Metabolism()()

Metastasis is the most important feature of gastric cancer (GC) and the most widely recognized reason for GC-related deaths. Unfortunately, the underlying mechanism behind this metastasis remains unknown. Mounting evidence suggests the dynamic regulatory role of sirtuin2 (SIRT2), a histone deacetyla...

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Detalles Bibliográficos
Autores principales: Li, Yang, Zhang, Mingming, Dorfman, Robert G., Pan, Yida, Tang, Dehua, Xu, Lei, Zhao, Zhenguo, Zhou, Qian, Zhou, Lixing, Wang, Yuming, Yin, Yuyao, Shen, Shanshan, Kong, Bo, Friess, Helmut, Zhao, Shimin, Wang, Lei, Zou, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005814/
https://www.ncbi.nlm.nih.gov/pubmed/29925042
http://dx.doi.org/10.1016/j.neo.2018.03.008