Expression of the Circadian Clock Gene BMAL1 Positively Correlates With Antitumor Immunity and Patient Survival in Metastatic Melanoma

INTRODUCTION: Melanoma is the most lethal type of skin cancer, with increasing incidence and mortality rates worldwide. Multiple studies have demonstrated a link between cancer development/progression and circadian disruption; however, the complex role of tumor-autonomous molecular clocks remains po...

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Detalles Bibliográficos
Autores principales: de Assis, Leonardo Vinícius Monteiro, Kinker, Gabriela Sarti, Moraes, Maria Nathália, Markus, Regina P., Fernandes, Pedro Augusto, Castrucci, Ana Maria de Lauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005821/
https://www.ncbi.nlm.nih.gov/pubmed/29946530
http://dx.doi.org/10.3389/fonc.2018.00185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005821/
https://www.ncbi.nlm.nih.gov/pubmed/29946530
http://dx.doi.org/10.3389/fonc.2018.00185

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