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The BCGΔBCG1419c Vaccine Candidate Reduces Lung Pathology, IL-6, TNF-α, and IL-10 During Chronic TB Infection

Mycobacterium tuberculosis (M. tuberculosis), the causative agent of human tuberculosis (TB), is estimated to be harbored by up to 2 billion people in a latent TB infection (LTBI) state. The only TB vaccine approved for use in humans, BCG, does not confer protection against establishment of or react...

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Detalles Bibliográficos
Autores principales: Flores-Valdez, Mario A., Pedroza-Roldán, César, Aceves-Sánchez, Michel de Jesús, Peterson, Eliza J. R., Baliga, Nitin S., Hernández-Pando, Rogelio, Troudt, JoLynn, Creissen, Elizabeth, Izzo, Linda, Bielefeldt-Ohmann, Helle, Bickett, Thomas, Izzo, Angelo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005825/
https://www.ncbi.nlm.nih.gov/pubmed/29946316
http://dx.doi.org/10.3389/fmicb.2018.01281