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Repeated Administration of D-Amphetamine Induces Distinct Alterations in Behavior and Metabolite Levels in 129Sv and Bl6 Mouse Strains

The main goal of the study was to characterize the behavioral and metabolomic profiles of repeated administration (for 11 days) of d-amphetamine (AMPH, 3 mg/kg i. p.), indirect agonist of dopamine (DA), in widely used 129S6/SvEvTac (129Sv) and C57BL/6NTac (Bl6) mouse strains. Acute administration of...

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Detalles Bibliográficos
Autores principales: Vanaveski, Taavi, Narvik, Jane, Innos, Jürgen, Philips, Mari-Anne, Ottas, Aigar, Plaas, Mario, Haring, Liina, Zilmer, Mihkel, Vasar, Eero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005828/
https://www.ncbi.nlm.nih.gov/pubmed/29946233
http://dx.doi.org/10.3389/fnins.2018.00399