Sex Differences in Healthspan Predict Lifespan in the 3xTg-AD Mouse Model of Alzheimer’s Disease

Mouse models of Alzheimer’s disease (AD) exhibit marked differences in life expectancy depending on their genotype and sex. The assessment of frailty could provide a measure of healthspan to facilitate comparisons between different AD models. We used a validated mouse frailty index (FI) assessment t...

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Detalles Bibliográficos
Autores principales: Kane, Alice E., Shin, Sooyoun, Wong, Aimee A., Fertan, Emre, Faustova, Natalia S., Howlett, Susan E., Brown, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005856/
https://www.ncbi.nlm.nih.gov/pubmed/29946252
http://dx.doi.org/10.3389/fnagi.2018.00172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005856/
https://www.ncbi.nlm.nih.gov/pubmed/29946252
http://dx.doi.org/10.3389/fnagi.2018.00172

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