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Sex Differences in Healthspan Predict Lifespan in the 3xTg-AD Mouse Model of Alzheimer’s Disease

Mouse models of Alzheimer’s disease (AD) exhibit marked differences in life expectancy depending on their genotype and sex. The assessment of frailty could provide a measure of healthspan to facilitate comparisons between different AD models. We used a validated mouse frailty index (FI) assessment t...

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Detalles Bibliográficos
Autores principales:	Kane, Alice E., Shin, Sooyoun, Wong, Aimee A., Fertan, Emre, Faustova, Natalia S., Howlett, Susan E., Brown, Richard E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005856/ https://www.ncbi.nlm.nih.gov/pubmed/29946252 http://dx.doi.org/10.3389/fnagi.2018.00172

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