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Efficient CRISPR-Cas9 Gene Disruption System in Edible-Medicinal Mushroom Cordyceps militaris

Cordyceps militaris is a well-known edible medicinal mushroom in East Asia that contains abundant and diverse bioactive compounds. Since traditional genome editing systems in C. militaris were inefficient and complicated, here, we show that the codon-optimized cas9, which was used with the newly rep...

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Detalles Bibliográficos
Autores principales: Chen, Bai-Xiong, Wei, Tao, Ye, Zhi-Wei, Yun, Fan, Kang, Lin-Zhi, Tang, Hong-Biao, Guo, Li-Qiong, Lin, Jun-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005869/
https://www.ncbi.nlm.nih.gov/pubmed/29946301
http://dx.doi.org/10.3389/fmicb.2018.01157