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Ligand-Induced Variations in Structural and Dynamical Properties Within an Enzyme Superfamily

Enzyme catalysis is a complex process involving several steps along the reaction coordinates, including substrate recognition and binding, chemical transformation, and product release. Evidence continues to emerge linking the functional and evolutionary role of conformational exchange processes in o...

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Detalles Bibliográficos
Autores principales: Narayanan, Chitra, Bernard, David N., Bafna, Khushboo, Gagné, Donald, Agarwal, Pratul K., Doucet, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005897/
https://www.ncbi.nlm.nih.gov/pubmed/29946547
http://dx.doi.org/10.3389/fmolb.2018.00054