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Effects of sildenafil and calcitonin gene-related peptide on brainstem glutamate levels: a pharmacological proton magnetic resonance spectroscopy study at 3.0 T

BACKGROUND: Studies involving human pharmacological migraine models have predominantly focused on the vasoactive effects of headache-inducing drugs, including sildenafil and calcitonin gene-related peptide (CGRP). However, the role of possible glutamate level changes in the brainstem and thalamus is...

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Detalles Bibliográficos
Autores principales: Younis, Samaira, Hougaard, Anders, Christensen, Casper Emil, Vestergaard, Mark Bitsch, Petersen, Esben Thade, Paulson, Olaf Bjarne, Larsson, Henrik Bo Wiberg, Ashina, Messoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005999/
https://www.ncbi.nlm.nih.gov/pubmed/29916084
http://dx.doi.org/10.1186/s10194-018-0870-2