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Lack of durable protection against cotton smoke-induced acute lung injury in sheep by nebulized single chain urokinase plasminogen activator or tissue plasminogen activator

BACKGROUND: Airway fibrin casts are clinically important complications of severe inhalational smoke-induced acute lung injury (ISIALI) for which reliable evidence-based therapy is lacking. Nebulized anticoagulants or a tissue plasminogen activator; tPA, has been advocated, but airway bleeding is a k...

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Detalles Bibliográficos
Autores principales: Fukuda, Satoshi, Enkhbaatar, Perenlei, Nelson, Christina, Cox, Robert A., Wolfson, Marla R., Shaffer, Thomas H., Williams, Robert O., Surasarang, Soraya Hengsawas, Sawittree, Sahakijpijarn, Florova, Galina, Komissarov, Andrey A., Koenig, Kathleen, Sarva, Krishna, Ndetan, Harrison T., Singh, Karan P., Idell, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006005/
https://www.ncbi.nlm.nih.gov/pubmed/29916009
http://dx.doi.org/10.1186/s40169-018-0196-3