Cargando…

The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow

The transition of hematopoiesis from the fetal liver (FL) to the bone marrow (BM) is incompletely characterized. We demonstrate that the Wiskott–Aldrich syndrome verprolin-homologous protein (WAVE) complex 2 is required for this transition, as complex degradation via deletion of its scaffold Hem-1 c...

Descripción completa

Detalles Bibliográficos
Autores principales: Shao, Lijian, Chang, Jianhui, Feng, Wei, Wang, Xiaoyan, Williamson, Elizabeth A., Li, Ying, Schajnovitz, Amir, Scadden, David, Mortensen, Luke J., Lin, Charles P., Li, Linheng, Paulson, Ariel, Downing, James, Zhou, Daohong, Hromas, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006146/
https://www.ncbi.nlm.nih.gov/pubmed/29915352
http://dx.doi.org/10.1038/s41467-018-04716-5