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The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow
The transition of hematopoiesis from the fetal liver (FL) to the bone marrow (BM) is incompletely characterized. We demonstrate that the Wiskott–Aldrich syndrome verprolin-homologous protein (WAVE) complex 2 is required for this transition, as complex degradation via deletion of its scaffold Hem-1 c...
Autores principales: | Shao, Lijian, Chang, Jianhui, Feng, Wei, Wang, Xiaoyan, Williamson, Elizabeth A., Li, Ying, Schajnovitz, Amir, Scadden, David, Mortensen, Luke J., Lin, Charles P., Li, Linheng, Paulson, Ariel, Downing, James, Zhou, Daohong, Hromas, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006146/ https://www.ncbi.nlm.nih.gov/pubmed/29915352 http://dx.doi.org/10.1038/s41467-018-04716-5 |
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