QSAR-based molecular signatures of prenylated (iso)flavonoids underlying antimicrobial potency against and membrane-disruption in Gram positive and Gram negative bacteria

Prenylated flavonoids and isoflavonoids are phytochemicals with remarkable antibacterial activity. In this study, 30 prenylated (iso)flavonoids were tested against Listeria monocytogenes and Escherichia coli (the latter in combination with an efflux pump inhibitor). Minimum inhibitory concentrations...

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Detalles Bibliográficos
Autores principales: Araya-Cloutier, Carla, Vincken, Jean-Paul, van de Schans, Milou G. M., Hageman, Jos, Schaftenaar, Gijs, den Besten, Heidy M. W., Gruppen, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006161/
https://www.ncbi.nlm.nih.gov/pubmed/29915354
http://dx.doi.org/10.1038/s41598-018-27545-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006161/
https://www.ncbi.nlm.nih.gov/pubmed/29915354
http://dx.doi.org/10.1038/s41598-018-27545-4

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