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IL-4 enhances survival of in vitro-differentiated mouse basophils through transcription-independent signaling downstream of PI3K
Interleukin 4 (IL-4) is a critical cytokine implicated with T(H)2 immune reactions, which are linked to pathologic conditions of allergic diseases. In that context, the initiation of T(H)2 responses can critically depend on early basophil-derived IL-4 to activate T-cell responses, which then amplify...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006176/ https://www.ncbi.nlm.nih.gov/pubmed/29915306 http://dx.doi.org/10.1038/s41419-018-0754-z |