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The Extract of Leonurus sibiricus Transgenic Roots with AtPAP1 Transcriptional Factor Induces Apoptosis via DNA Damage and Down Regulation of Selected Epigenetic Factors in Human Cancer Cells

The aim of this study was to determine the anticancer potential of Leonurus sibiricus extract derived from in vitro transgenic roots transformed by Agrobacetrium rhizogenes with AtPAP1 transcriptional factor, and that of transformed roots without construct, on grade IV human glioma cells and the U87...

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Detalles Bibliográficos
Autores principales: Sitarek, Przemysław, Kowalczyk, Tomasz, Santangelo, Simona, Białas, Adam J., Toma, Monika, Wieczfinska, Joanna, Śliwiński, Tomasz, Skała, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006195/
https://www.ncbi.nlm.nih.gov/pubmed/29786770
http://dx.doi.org/10.1007/s11064-018-2551-6