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The Extract of Leonurus sibiricus Transgenic Roots with AtPAP1 Transcriptional Factor Induces Apoptosis via DNA Damage and Down Regulation of Selected Epigenetic Factors in Human Cancer Cells
The aim of this study was to determine the anticancer potential of Leonurus sibiricus extract derived from in vitro transgenic roots transformed by Agrobacetrium rhizogenes with AtPAP1 transcriptional factor, and that of transformed roots without construct, on grade IV human glioma cells and the U87...
Autores principales: | Sitarek, Przemysław, Kowalczyk, Tomasz, Santangelo, Simona, Białas, Adam J., Toma, Monika, Wieczfinska, Joanna, Śliwiński, Tomasz, Skała, Ewa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006195/ https://www.ncbi.nlm.nih.gov/pubmed/29786770 http://dx.doi.org/10.1007/s11064-018-2551-6 |
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