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ERK 1/2 Activation Mediates the Neuroprotective Effect of BpV(pic) in Focal Cerebral Ischemia–Reperfusion Injury

Bisperoxovanadium (pyridine-2-carboxyl) [bpV(pic)] is a commercially available PTEN inhibitor. Previous studies from us and others have shown that bpV(pic) confers neuroprotection in cerebral ischemia injury. We set up to determine whether ERK 1/2 activation plays a role in bpV(pic)-induced neuropro...

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Detalles Bibliográficos
Autores principales: Liu, Rui, Tang, Jun-Chun, Pan, Meng-Xian, Zhuang, Yang, Zhang, Ya, Liao, Hua-Bao, Zhao, Dan, Lei, Yang, Lei, Rui-Xue, Wang, Shu, Liu, An-Chun, Qin, Xing-Ping, Chen, Juan, Zhang, Zhi-Feng, Wan, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006215/
https://www.ncbi.nlm.nih.gov/pubmed/29882124
http://dx.doi.org/10.1007/s11064-018-2558-z