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The unique fold and lability of the [2Fe-2S] clusters of NEET proteins mediate their key functions in health and disease

ABSTRACT: NEET proteins comprise a new class of [2Fe-2S] cluster proteins. In human, three genes encode for NEET proteins: cisd1 encodes mitoNEET (mNT), cisd2 encodes the Nutrient-deprivation autophagy factor-1 (NAF-1) and cisd3 encodes MiNT (Miner2). These recently discovered proteins play key role...

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Detalles Bibliográficos
Autores principales: Karmi, Ola, Marjault, Henri-Baptiste, Pesce, Luca, Carloni, Paolo, Onuchic, Jose’ N., Jennings, Patricia A., Mittler, Ron, Nechushtai, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006223/
https://www.ncbi.nlm.nih.gov/pubmed/29435647
http://dx.doi.org/10.1007/s00775-018-1538-8