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Chimeric antigen receptor T‑cell therapy—a hematological success story

Chimeric antigen receptor (CAR) T cells are genetically engineered autologous cells that express an activating receptor targeted towards one or more tumoral antigens. After ex vivo production and re-infusion, they are able to proliferate in the host and to recognize and kill tumor cells. Together wi...

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Detalles Bibliográficos
Autores principales: Wohlfarth, Philipp, Worel, Nina, Hopfinger, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006225/
https://www.ncbi.nlm.nih.gov/pubmed/29983827
http://dx.doi.org/10.1007/s12254-018-0409-x