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Regulatory T cells control endothelial chemokine production and migration of T cells into intestinal tumors of APC(min/+) mice

Tumor-infiltrating lymphocytes are crucial for anti-tumor immunity. We have previously shown that regulatory T cells (Treg) are able to reduce T-cell transendothelial migration in vitro and accumulation of effector T cells in intestinal tumors in vivo. Treg depletion also resulted in increased level...

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Detalles Bibliográficos
Autores principales: Akeus, Paulina, Szeponik, Louis, Ahlmanner, Filip, Sundström, Patrik, Alsén, Samuel, Gustavsson, Bengt, Sparwasser, Tim, Raghavan, Sukanya, Quiding-Järbrink, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006230/
https://www.ncbi.nlm.nih.gov/pubmed/29671006
http://dx.doi.org/10.1007/s00262-018-2161-9