Kcnn4 is a modifier gene of intestinal cystic fibrosis preventing lethality in the Cftr-F508del mouse

Nearly 70% of cystic fibrosis (CF) patients bear the phenylalanine-508 deletion but disease severity differs greatly, and is not explained by the existence of different mutations in compound heterozygous. Studies demonstrated that genes other than CFTR relate to intestinal disease in humans and CF-m...

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Detalles Bibliográficos
Autores principales: Philp, Amber R., Riquelme, Texia T., Millar-Büchner, Pamela, González, Rodrigo, Sepúlveda, Francisco V., Cid, L. Pablo, Flores, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006244/
https://www.ncbi.nlm.nih.gov/pubmed/29915289
http://dx.doi.org/10.1038/s41598-018-27465-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006244/
https://www.ncbi.nlm.nih.gov/pubmed/29915289
http://dx.doi.org/10.1038/s41598-018-27465-3

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