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Presymptomatic change in microRNAs modulates Tau pathology

MicroRNAs (miRs) are 18~23 nucleotides long non-coding RNAs that regulate gene expression. To explore whether miR alterations in tauopathy contribute to pathological conditions, we first determined which hippocampal miRs are altered at the presymptomatic and symptomatic stages of tauopathy using rTg...

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Detalles Bibliográficos
Autores principales: Sharma, Salil, Khadimallah, Ines, Corya, Adam Williamson, Ali, Yousuf Omar, Rao, Xi, Liu, Yunlong, Lu, Hui-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006352/
https://www.ncbi.nlm.nih.gov/pubmed/29915328
http://dx.doi.org/10.1038/s41598-018-27527-6