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Liver X receptors regulate hepatic F4/80(+)CD11b(+) Kupffer cells/macrophages and innate immune responses in mice

The liver X receptors (LXRs), LXRα and LXRβ, are nuclear receptors that regulate lipid homeostasis. LXRs also regulate inflammatory responses in cultured macrophages. However, the role of LXRs in hepatic immune cells remains poorly characterized. We investigated the role of LXRs in regulation of inf...

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Detalles Bibliográficos
Autores principales: Endo-Umeda, Kaori, Nakashima, Hiroyuki, Komine-Aizawa, Shihoko, Umeda, Naoki, Seki, Shuhji, Makishima, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006359/
https://www.ncbi.nlm.nih.gov/pubmed/29915246
http://dx.doi.org/10.1038/s41598-018-27615-7