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Liver X receptors regulate hepatic F4/80(+)CD11b(+) Kupffer cells/macrophages and innate immune responses in mice
The liver X receptors (LXRs), LXRα and LXRβ, are nuclear receptors that regulate lipid homeostasis. LXRs also regulate inflammatory responses in cultured macrophages. However, the role of LXRs in hepatic immune cells remains poorly characterized. We investigated the role of LXRs in regulation of inf...
Autores principales: | Endo-Umeda, Kaori, Nakashima, Hiroyuki, Komine-Aizawa, Shihoko, Umeda, Naoki, Seki, Shuhji, Makishima, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006359/ https://www.ncbi.nlm.nih.gov/pubmed/29915246 http://dx.doi.org/10.1038/s41598-018-27615-7 |
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