Electrical properties, substrate specificity and optogenetic potential of the engineered light-driven sodium pump eKR2

A new microbial rhodopsin class that actively transports sodium out of the cell upon illumination was described in 2013. However, poor membrane targeting of the first-identified sodium pump KR2 in mammalian cells has hindered the direct electrical investigation of its transport mechanism and optogen...

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Detalles Bibliográficos
Autores principales: Grimm, Christiane, Silapetere, Arita, Vogt, Arend, Bernal Sierra, Yinth Andrea, Hegemann, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006383/
https://www.ncbi.nlm.nih.gov/pubmed/29915394
http://dx.doi.org/10.1038/s41598-018-27690-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006383/
https://www.ncbi.nlm.nih.gov/pubmed/29915394
http://dx.doi.org/10.1038/s41598-018-27690-w

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