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Prediction and identification of transcriptional regulatory elements at the lung cancer-specific DKK1 locus

The glycoprotein dickkopf 1 (DKK1) is highly expressed in lung cancer cell lines and tissues. Our previous study demonstrated that DKK1 promoter activity is low in lung cancer cell lines. This may be because it lacks the necessary transcriptional regulatory elements (TREs) required for higher activi...

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Detalles Bibliográficos
Autores principales: Gao, Yan, Du, Xian, Zeng, Jing, Wu, Ruimin, Chen, Yijia, Li, Fuyan, Li, Wei, Zhou, Hong, Yang, Yi, Pei, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006444/
https://www.ncbi.nlm.nih.gov/pubmed/29928394
http://dx.doi.org/10.3892/ol.2018.8638