Small molecule regulated dynamic structural changes of human G-quadruplexes

The changes in structure and dynamics of oncogenic (c-MYC) and telomeric (h-TELO) G-rich DNA sequences due to the binding of a novel carbazole derivative (BTC) are elucidated using single-molecule Förster resonance energy transfer (sm-FRET), fluorescence correlation spectroscopy (FCS) and NMR spectr...

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Detalles Bibliográficos
Autores principales: Debnath, Manish, Ghosh, Shirsendu, Panda, Deepanjan, Bessi, Irene, Schwalbe, Harald, Bhattacharyya, Kankan, Dash, Jyotirmayee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006475/
https://www.ncbi.nlm.nih.gov/pubmed/29997820
http://dx.doi.org/10.1039/c6sc00057f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006475/
https://www.ncbi.nlm.nih.gov/pubmed/29997820
http://dx.doi.org/10.1039/c6sc00057f

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