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Small molecule regulated dynamic structural changes of human G-quadruplexes

The changes in structure and dynamics of oncogenic (c-MYC) and telomeric (h-TELO) G-rich DNA sequences due to the binding of a novel carbazole derivative (BTC) are elucidated using single-molecule Förster resonance energy transfer (sm-FRET), fluorescence correlation spectroscopy (FCS) and NMR spectr...

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Detalles Bibliográficos
Autores principales:	Debnath, Manish, Ghosh, Shirsendu, Panda, Deepanjan, Bessi, Irene, Schwalbe, Harald, Bhattacharyya, Kankan, Dash, Jyotirmayee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2016
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006475/ https://www.ncbi.nlm.nih.gov/pubmed/29997820 http://dx.doi.org/10.1039/c6sc00057f

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