Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer

PARP inhibitors have been widely tested in clinical trials, especially for the treatment of breast cancer and ovarian cancer, and were shown to be highly successful. Because PARP primarily functions in sensing and repairing DNA strand breaks, the therapeutic effect of PARP inhibition is generally be...

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Detalles Bibliográficos
Autores principales: Hou, Dong, Liu, Zhaojian, Xu, Xiuhua, Liu, Qiao, Zhang, Xiyu, Kong, Beihua, Wei, Jian-Jun, Gong, Yaoqin, Shao, Changshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006521/
https://www.ncbi.nlm.nih.gov/pubmed/29684820
http://dx.doi.org/10.1016/j.redox.2018.03.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006521/
https://www.ncbi.nlm.nih.gov/pubmed/29684820
http://dx.doi.org/10.1016/j.redox.2018.03.016

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