High circulatory leptin mediated NOX-2-peroxynitrite-miR21 axis activate mesangial cells and promotes renal inflammatory pathology in nonalcoholic fatty liver disease

High circulatory insulin and leptin followed by underlying inflammation are often ascribed to the ectopic manifestations in non-alcoholic fatty liver disease (NAFLD) but the exact molecular pathways remain unclear. We have shown previously that CYP2E1-mediated oxidative stress and circulating leptin...

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Detalles Bibliográficos
Autores principales: Alhasson, Firas, Seth, Ratanesh Kumar, Sarkar, Sutapa, Kimono, Diana A., Albadrani, Muayad S., Dattaroy, Diptadip, Chandrashekaran, Varun, Scott, Geoffrey I., Raychoudhury, Samir, Nagarkatti, Mitzi, Nagarkatti, Prakash, Diehl, Anna Mae, Chatterjee, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006523/
https://www.ncbi.nlm.nih.gov/pubmed/29660503
http://dx.doi.org/10.1016/j.redox.2018.04.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006523/
https://www.ncbi.nlm.nih.gov/pubmed/29660503
http://dx.doi.org/10.1016/j.redox.2018.04.002

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