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Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks
BACKGROUND: Human induced pluripotent stem (iPS) cells have revolutionised research and spark hopes for future tissue replacement therapies. To obtain high cell numbers, iPS cells can be expanded indefinitely. However, as long-term expansion can compromise cell integrity and quality, we set out to a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006556/ https://www.ncbi.nlm.nih.gov/pubmed/29914569 http://dx.doi.org/10.1186/s13287-018-0893-2 |