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Differentially methylated regions in T cells identify kidney transplant patients at risk for de novo skin cancer

BACKGROUND: Cutaneous squamous cell carcinoma (cSCC) occurs 65–200 times more in immunosuppressed organ transplant patients than in the general population. T cells, which are targeted by the given immunosuppressive drugs, are involved in anti-tumor immune surveillance and are functionally regulated...

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Detalles Bibliográficos
Autores principales: Peters, Fleur S., Peeters, Annemiek M. A., Mandaviya, Pooja R., van Meurs, Joyce B. J., Hofland, Leo J., van de Wetering, Jacqueline, Betjes, Michiel G. H., Baan, Carla C., Boer, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006560/
https://www.ncbi.nlm.nih.gov/pubmed/29946375
http://dx.doi.org/10.1186/s13148-018-0519-7