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Differentially methylated regions in T cells identify kidney transplant patients at risk for de novo skin cancer
BACKGROUND: Cutaneous squamous cell carcinoma (cSCC) occurs 65–200 times more in immunosuppressed organ transplant patients than in the general population. T cells, which are targeted by the given immunosuppressive drugs, are involved in anti-tumor immune surveillance and are functionally regulated...
Autores principales: | Peters, Fleur S., Peeters, Annemiek M. A., Mandaviya, Pooja R., van Meurs, Joyce B. J., Hofland, Leo J., van de Wetering, Jacqueline, Betjes, Michiel G. H., Baan, Carla C., Boer, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006560/ https://www.ncbi.nlm.nih.gov/pubmed/29946375 http://dx.doi.org/10.1186/s13148-018-0519-7 |
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