Performance of epistasis detection methods in semi-simulated GWAS

BACKGROUND: Part of the missing heritability in Genome Wide Association Studies (GWAS) is expected to be explained by interactions between genetic variants, also called epistasis. Various statistical methods have been developed to detect epistasis in case-control GWAS. These methods face major stati...

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Detalles Bibliográficos
Autores principales: Chatelain, Clément, Durand, Guillermo, Thuillier, Vincent, Augé, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006572/
https://www.ncbi.nlm.nih.gov/pubmed/29914375
http://dx.doi.org/10.1186/s12859-018-2229-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006572/
https://www.ncbi.nlm.nih.gov/pubmed/29914375
http://dx.doi.org/10.1186/s12859-018-2229-8

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