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Performance of epistasis detection methods in semi-simulated GWAS
BACKGROUND: Part of the missing heritability in Genome Wide Association Studies (GWAS) is expected to be explained by interactions between genetic variants, also called epistasis. Various statistical methods have been developed to detect epistasis in case-control GWAS. These methods face major stati...
Autores principales: | Chatelain, Clément, Durand, Guillermo, Thuillier, Vincent, Augé, Franck |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006572/ https://www.ncbi.nlm.nih.gov/pubmed/29914375 http://dx.doi.org/10.1186/s12859-018-2229-8 |
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