Oxidative stress-induced chromosome breaks within the ABL gene: a model for chromosome rearrangement in nasopharyngeal carcinoma

BACKGROUND: The mechanism underlying chromosome rearrangement in nasopharyngeal carcinoma (NPC) remains elusive. It is known that most of the aetiological factors of NPC trigger oxidative stress. Oxidative stress is a potent apoptotic inducer. During apoptosis, chromatin cleavage and DNA fragmentati...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Sang-Nee, Sim, Sai-Peng, Khoo, Alan Soo-Beng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006577/
https://www.ncbi.nlm.nih.gov/pubmed/29914565
http://dx.doi.org/10.1186/s40246-018-0160-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006577/
https://www.ncbi.nlm.nih.gov/pubmed/29914565
http://dx.doi.org/10.1186/s40246-018-0160-8

Ejemplares similares