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rs10732516 polymorphism at the IGF2/H19 locus associates with genotype-specific effects on placental DNA methylation and birth weight of newborns conceived by assisted reproductive technology

BACKGROUND: Assisted reproductive technology (ART) has been associated with low birth weight of fresh embryo transfer (FRESH) derived and increased birth weight of frozen embryo transfer (FET)-derived newborns. Owing to that, we focused on imprinted insulin-like growth factor 2 (IGF2)/H19 locus know...

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Detalles Bibliográficos
Autores principales: Marjonen, Heidi, Auvinen, Pauliina, Kahila, Hanna, Tšuiko, Olga, Kõks, Sulev, Tiirats, Airi, Viltrop, Triin, Tuuri, Timo, Söderström-Anttila, Viveca, Suikkari, Anne-Maria, Salumets, Andres, Tiitinen, Aila, Kaminen-Ahola, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006593/
https://www.ncbi.nlm.nih.gov/pubmed/29946374
http://dx.doi.org/10.1186/s13148-018-0511-2